Oklahoma Farm Report masthead graphic with wheat on the left and cattle on the right.
Howdy Neighbors!
Ron Hays, Director of Farm and Ranch Programming, Radio Oklahoma Ag Network  |  2401 Exchange Ave, Suite F, Oklahoma City, Ok 73108  |  (405) 601-9211


Agricultural News

OSU Scientists Helping to Seek Cure for Tuberculosis

Thu, 06 Oct 2022 12:11:39 CDT

OSU Scientists Helping to Seek Cure for Tuberculosis Oklahoma State University and the Oklahoma Center for Respiratory and Infectious Diseases (OCRID) are teaming up through a National Institutes of Health grant to take the first steps in curing Mycobacterium tuberculosis.

Tuberculosis is one of the deadliest infections in the world with 10 million active infections each year and 1.4 million deaths in 2019, according to the World Health Organization.

“It is important to understand the mechanism that causes TB in humans. We are studying how immune cells fight against tuberculosis,” said Yong Cheng, an assistant professor in the OSU Department of Biochemistry and Molecular Biology. “Additionally, to better control global TB spread, it is necessary to understand immune defense. The focus of our study is to understand the immune response in humans as a means to cure TB.”

Both the immune system and the bacteria that cause TB determine the outcome of the infection, according to Cheng. The long-term goal of the study in his laboratory is to identify host lncRNAs that are beneficial to immune defense against TB infection and to further understand how lncRNAs help regulate host immunity.

Data from previous research showed that a group of host molecules called long noncoding RNAs (lncRNAs) plays an important role in the immune defense of microbial infections, but there is limited knowledge on their role when it comes to TB specifically.

OCRID recently developed a gene-editing screening technique to study lncRNAs in human cells.

“In collaboration with them, we are using this new technique to identify host molecules that can activate the immune response to kill Mycobacterium tuberculosis,” Cheng said. “Our aim is to screen and develop new therapeutic tools and techniques that can be used to treat TB disease in humans.”

Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under award number 1R21AI166118-01A1 through the exploratory/developmental research grant (R21). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The project is also supported by the OCRID CoBRE grant and the OCRID center mentorship program, which provides training and mentoring to junior faculty and the next generation of scientists.



WebReadyTM Powered by WireReady® NSI


Top Agricultural News

  • Oklahoma Youth Expo Sale of Champions Sale Order Available Here- Sale Set for 4 PM Friday  Fri, 17 Mar 2023 04:50:54 CDT
  • Rural Voters Dominated Vote to Defeat Recreational Marijuana March 7th  Fri, 10 Mar 2023 07:13:05 CST
  • Ron Hays Talks to Israeli Ag Tour Guide Colin Lotzof About the Miraclel of Ag in Israel  Wed, 22 Feb 2023 22:11:04 CST
  • OALP Members Experience First Hand View of Cutting Edge Drip Irrigation Technology as Israel Travel Ends  Wed, 22 Feb 2023 10:51:49 CST
  • OALP Members Get First Hand View of Cutting Edge Drip Irrigation Technology as Israel Travel Ends  Wed, 22 Feb 2023 10:50:10 CST
  • Oklahoma Ag Leadership Program Sees Fruit, Beef and Dairy Production North of the Sea of Galilee in Israel  Mon, 20 Feb 2023 21:56:02 CST
  • Oklahoma Ag Leadership Program Sees Diverse Farm Operations in Jordan River Valley of Israel  Sun, 19 Feb 2023 21:17:30 CST
  • Israeli Tour Guide Mark Kedem Talks About The Cultural Aspects of What Class XX of OALP is Experiencing   Sat, 18 Feb 2023 22:17:23 CST

  • More Headlines...


    Ron salutes our daily email sponsors!

    Oklahoma Beef council Oklahoma Ag Credit Oklahoma Farm Bureau National Livestock Credit Ag Mediation Program P&K Equipment Oklahoma City Farm Show Union Mutual Stillwater Milling Oklahoma Cattlemen's Association KIS FUTURES, INC.

    Search OklahomaFarmReport.com

    © 2008-2024 Oklahoma Farm Report
    Email Ron   |   Newsletter Signup   |    Current Spots   |    Program Links

    WebReady powered by WireReady® Inc.